It is important to continue taking your malaria prophylaxis drug after you leave the area where malaria occurs, because the parasite may still be in your blood and could cause malaria weeks or months after you return home.

Recommendation from the US Centers of Disease Control:

Travelers should be advised to start chemoprophylaxis before travel and to use prophylaxis continuously while in malaria-endemic areas and after leaving malaria areas

• 4 weeks for doxycycline, or mefloquine
• 7 days for Malarone (atovaquone/proguanil) or primaquine

(CDC Yellow Book, Malaria)

 

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